Search results for "Complete genome sequences"

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High-throughput sequencing (HTS) for the analysis of viral populations

2020

The development of High-Throughput Sequencing (HTS) technologies is having a major impact on the genomic analysis of viral populations. Current HTS platforms can capture nucleic acid variation across millions of genes for both selected amplicons and full viral genomes. HTS has already facilitated the discovery of new viruses, hinted new taxonomic classifications and provided a deeper and broader understanding of their diversity, population and genetic structure. Hence, HTS has already replaced standard Sanger sequencing in basic and applied research fields, but the next step is its implementation as a routine technology for the analysis of viruses in clinical settings. The most likely appli…

0301 basic medicineMicrobiology (medical)030106 microbiologyPopulationGenomicsComputational biologyGenome ViralBiologyEnvironmentMicrobiologyDNA sequencingDisease OutbreaksPopulation genomicsEvolution Molecular03 medical and health sciencessymbols.namesakeGeneticsAnimalsHumanseducationMolecular BiologyEcology Evolution Behavior and SystematicsSanger sequencingeducation.field_of_studyClinical virologyOutbreaksComputational BiologyHigh-Throughput Nucleotide Sequencing030104 developmental biologyInfectious DiseasesGenetics PopulationMolecular Diagnostic TechniquesVirus DiseasesVirusessymbolsMetagenomeMolecular evolutionGene-Environment InteractionNanopore sequencingMetagenomicsTransmission clustersPopulation genomicsClinical virologyComplete genome sequencesSingle molecule real time sequencing
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